Viscoelasticity Parameters of Hifu Ablated Canine Liver Tissues Ex Vivo

Ex Vivo characterization of canine liver tissue viscoelasticity after high-intensity focused ultrasound ablation.

The potential of elasticity imaging to detect high-intensity focused ultrasound (HIFU) lesions on the basis of their distinct biomechanical properties is promising. However, information on the quantitative mechanical properties of the tissue and the optimal intensity at which to determine the best contrast parameters is scarce. In this study, fresh canine livers were ablated using combinations ...

Potential Strong-hifu-ablation-induced Tissue Damage as Measured by Viscoelastic Characterization of Canine Liver Tissue Post-ablation

Objective: High Intensity Focused Ultrasound (HIFU) has been shown capable of ablating soft tissues in vitro and in vivo. However, mainly due to the lack of knowledge of the exerted radiation force in tissue, mechanical characterization of ablated tissues, particularly at very high HIFU powers, remains largely understudied. This study aims at quantifying the canine liver tissue viscoelastic pro...

Boiling histotripsy lesion characterization on a clinical magnetic resonance imaging-guided high intensity focused ultrasound system

PURPOSE High intensity focused ultrasound (HIFU) is a non-invasive therapeutic technique that can thermally ablate tumors. Boiling histotripsy (BH) is a HIFU approach that can emulsify tissue in a few milliseconds. Lesion volume and temperature effects for different BH sonication parameters are currently not well characterized. In this work, lesion volume, temperature distribution, and area of ...

Title: Ex Vivo Characterization of Canine Liver Tissue Viscoelasticity Following High Intensity

High intensity focused ultrasound (HIFU) focal spot localization using harmonic motion imaging (HMI).

Several ultrasound-based imaging modalities have been proposed for image guidance and monitoring of high-intensity focused ultrasound (HIFU) treatment. However, accurate localization and characterization of the effective region of treatment (focal spot) remain important obstacles in the clinical implementation of HIFU ablation. Harmonic motion imaging for focused ultrasound (HMIFU) is a HIFU mo...